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Home/Compounds/API/(RS)-cyclophosphamide
C7H15Cl2N2O2P
261.08 g/mol
APIDanger

Cyclophosphamide

CAS50-18-0EC200-015-4
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Cyclophosphamide is a compound used as an alkylating agent in pharmaceutical manufacturing. It has been identified as a substance that can cause cancer and reproductive toxicity based on authoritative health evaluations.

Pharmaceutical raw material for antineoplastic productsImmunosuppressant drug substance

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Restricted or banned substances

Substances on this list are banned or restricted under the named regulation. This page is a compliance reference — verify your obligations under applicable law.

Relevant lists:California Proposition 65

CAS 50-18-0

Related Compounds

StrongSame Parent

Cyclophosphamide hydrate

CAS6055-19-2

pharmaceutical raw material

ReferenceSame Category

Corticosterone

CAS50-22-6

pharmaceutical raw material

ReferenceSame Category

Cortisol

CAS50-23-7

pharmaceutical raw material

ReferenceSame Category

Prednisolone

CAS50-24-8

pharmaceutical raw material

ReferenceSame Category

Estriol

CAS50-27-1

pharmaceutical raw material

Referencesame scaffold

3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide

CAS72578-71-3

pharmaceutical intermediate

Referencesame scaffold

Ifosfamide

CAS3778-73-2

pharmaceutical raw material

Safety Reference

Corrosive
Corrosive
Toxic
Toxic
Harmful
Harmful
Health Hazard
Health Hazard
Danger
H301Toxic if swallowed
H302Harmful if swallowed
H318Causes serious eye damage
H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H362May cause harm to breast-fed children
H370Causes damage to organs
Regulatory Compliance1
  • California Proposition 65USRegulation
    Listed· listed since 1987-02-27Source

Customs Tariff Classification

The international HS code for Cyclophosphamide (CAS 50-18-0) is 2934.99.

HS code (international, 6-digit)

2934.99

EU CN code (8-digit)

2934 99 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

N,N-bis(2-chloroethyl)-2-oxo-1,3,2lambda5-oxazaphosphinan-2-amine

InChIKey

CMSMOCZEIVJLDB-UHFFFAOYSA-N

SMILES

C1CNP(=O)(OC1)N(CCCl)CCCl

Synonyms (95)
  • ASTA
  • B518
  • Ciclofosfamida [INN-Spanish]
  • Cyclophosphamide (INN)
  • Cyclophosphamidum [INN-Latin]
  • (RS)-Cyclophosphamide
  • 50-18-0 (anhydrous)
  • Anhydrous cyclophosphamide
  • Asta B 518
  • CP monohydrate
  • CYCLO-cell
  • CYCLOPHOSPAMIDE MONOHYDRATE
  • CYCLOPHOSPHAMIDE LYOPHILIZED
  • Carloxan
  • Ciclofosfamida
  • Ciclofosfamide
  • Ciclophosphamide
  • Cicloxal
  • Clafen
  • Claphene
  • Cycloblastin
  • Cycloblastine
  • Cyclofosphamide
  • Cyclophospham
  • Cyclophosphamid
  • Cyclophosphamide anhydrous
  • Cyclophosphamidum
  • Cyclophosphan
  • Cyclophosphane
  • Cyclophosphanum
  • Cyclophosphoramide
  • Cyclostin
  • Cyclostine
  • Cyklofosfamid
  • Cyklofosfamid [Czech]
  • Cytophosphan
  • Cytophosphane
  • Cytoxan
  • Cytoxan (Lyophilized)
  • Cytoxan (TN)
  • D,L-Cyclophosphamide
  • Endoxan
  • Endoxan R
  • Endoxan monohydrate
  • Endoxan-Asta
  • Endoxana
  • Endoxanal
  • Endoxane
  • Enduxan
  • Fosfaseron
  • Frindovyx
  • Genoxal
  • Genuxal
  • Ledoxina
  • Lyophilized Cytoxan
  • Mitoxan
  • Procytox
  • Revimmune
  • Semdoxan
  • Sendoxan
  • Senduxan
  • Syklofosfamid
  • Zyklophosphamid
  • Zyklophosphamid [German]
  • cyclophosphamide