C22H21ClO3
368.9 g/mol
Research ReagentWarning
4,4',4''-Trimethoxytrityl chloride
CAS49757-42-8EC256-474-6
Category
Research Reagent
Compound Class
Halocarbon
Primary Use
Research Compound
4,4',4''-Trimethoxytrityl chloride is a chemical compound used as a protecting group reagent for alcohols in organic synthesis. It features a trityl core with three methoxy substituents, providing stability and selectivity for protecting hydroxyl groups during complex molecule assembly.
Protecting group reagent for alcohols in organic synthesisLaboratory reagent for research purposes
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.83
4-Methoxytriphenylmethyl chloride
CAS14470-28-1
pharmaceutical intermediate
SimilarStructure SimilarSimilarity 0.83
4,4'-Dimethoxytrityl chloride
CAS40615-36-9
protecting group reagent
ApplicationSame Use
Triphenylmethyl chloride
CAS76-83-5
research compound
ReferenceSame Category
Tert-Butyl imidazole-1-carboxylate
CAS49761-82-2
research compound
ReferenceSame Category
Nipecotic acid
CAS498-95-3
research compound
ReferenceSame Category
4-hydroxy-3-methylbenzoic acid
CAS499-76-3
research compound
ReferenceSame Category
Lutidinic acid
CAS499-80-9
research compound
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for 4,4',4''-Trimethoxytrityl chloride (CAS 49757-42-8) is 2909.30.
HS code (international, 6-digit)
2909.30
EU CN code (8-digit)
2909 30 90
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
1-[chloro-bis(4-methoxyphenyl)methyl]-4-methoxybenzene
InChIKey
OBFCMKPFILBCSQ-UHFFFAOYSA-N
SMILES
COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)Cl
Synonyms (11)
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