Home/Compounds/Pharmaceutical Intermediate/5-O-ethyl 7-O-methyl 6-(2-chlorophenyl)-8-methyl-3,4,6,7-tetrahydro-2H-1,4-benzoxazine-5,7-dicarboxylate
C20H22ClNO5
391.8 g/mol
Pharmaceutical IntermediateWarning
5-O-ethyl 7-O-methyl 6-(2-chlorophenyl)-8-methyl-3,4,6,7-tetrahydro-2H-1,4-benzoxazine-5,7-dicarboxylate
CAS496024-43-2EC991-762-1
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate
This compound is a substituted benzoxazine dicarboxylate used as a pharmaceutical intermediate in the synthesis of amlodipine analogues. It features a complex polycyclic structure with ester, amine, and ether functional groups, making it a key building block for calcium channel blocker derivatives.
pharmaceutical intermediate for amlodipine analogue synthesisresearch compound for calcium channel blocker development
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H373May cause damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
5-O-ethyl 7-O-methyl 6-(2-chlorophenyl)-8-methyl-3,4,6,7-tetrahydro-2H-1,4-benzoxazine-5,7-dicarboxylate
InChIKey
ZTKBXGUJDFQQPS-UHFFFAOYSA-N
SMILES
CCOC(=O)C1=C2C(=C(C(C1C3=CC=CC=C3Cl)C(=O)OC)C)OCCN2
Synonyms (11)
- 2H-1,4-Benzoxazine-5,7-dicarboxylic acid, 6-(2-chlorophenyl)-3,4,6,7-tetrahydro-8-methyl-, 5-ethyl 7-methyl ester; 5-Ethyl 7-methyl 6-(2-chlorophenyl)-3,4,6,7-tetrahydro-8-methyl-2H-1,4-benzoxazine-5,7-dicarboxylate; 5-Ethyl 7-methyl 6-(2-chlorophenyl)-8-methyl-3,4,6,7-tetrahydro-2H-1,4-benzo[b][1,4]oxazine-5,7-dicarboxylate; Propofol EP Impurity D
- Amlodipine Impurity 1
- Amlodipine Impurity 2
- Amlodipine Impurity 30
- Amlodipine Impurity 31
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