Home/Compounds/Pharmaceutical Intermediate/(2S,4S)-4-Cyano-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl) 2-methyl ester
C12H18N2O4
254.28 g/mol
Pharmaceutical IntermediateDanger
1,2-Pyrrolidinedicarboxylic acid, 4-cyano-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4S)-
CAS487048-28-2EC688-361-6
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate
This compound is a pharmaceutical intermediate used in the synthesis of Velpatasvir. It features a pyrrolidine ring with ester, ether, and nitrile functional groups, and has moderate polarity and low molecular weight.
Pharmaceutical intermediate for Velpatasvir manufacturingResearch compound for hepatitis C virus inhibitor development
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 487048-28-2
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Safety Reference
Danger
H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
1-O-tert-butyl 2-O-methyl (2S,4S)-4-cyanopyrrolidine-1,2-dicarboxylate
InChIKey
GHLKJIQVORAVHE-BDAKNGLRSA-N
SMILES
CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)OC)C#N
Synonyms (10)
- Boc-cis-4-CN-Pro-OMe