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Home/Compounds/Pharmaceutical Intermediate/Boc-Glycine
C7H13NO4
175.18 g/mol
Pharmaceutical IntermediateDanger

Boc-glycine

CAS4530-20-5EC224-864-5
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

Boc-glycine is a chemical compound widely used as a protecting reagent for the amino group in peptide synthesis. Its primary significance lies in enabling the selective protection and deprotection of glycine during the manufacturing of pharmaceutical intermediates and research peptides.

amino acid protecting reagent in peptide synthesispharmaceutical intermediate for peptide-based drug manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Reading

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2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

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Safety Reference

Corrosive
Corrosive
Harmful
Harmful
Danger
H302Harmful if swallowed
H318Causes serious eye damage

Customs Tariff Classification

The international HS code for Boc-glycine (CAS 4530-20-5) is 2924.19.

HS code (international, 6-digit)

2924.19

EU CN code (8-digit)

2924 19 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

2-[(2-methylpropan-2-yl)oxycarbonylamino]acetic acid

InChIKey

VRPJIFMKZZEXLR-UHFFFAOYSA-N

SMILES

CC(C)(C)OC(=O)NCC(=O)O

Synonyms (45)
  • BOC-GLY
  • (tert-butoxycarbonyl)glycine
  • BOC-L-GLYCINE
  • Boc-Gly-OH
  • Boc-Gly-OH, >=99.0% (T)
  • Boc-Glycine OH
  • Boc-glycine
  • Glycine, N-tert-butyl ester
  • N-(Carbo-tert-butoxy)glycine
  • N-Boc-Gly
  • N-Boc-Gly-OH
  • N-Boc-L-glycine
  • N-Boc-glycine
  • N-alpha-t-Boc-glycine
  • N-t-Boc-glycine
  • N-t-Butoxycarbonylglycine
  • N-t-Butyloxycarbonyl glycine
  • N-tert-Boc-glycine-OH
  • Nalpha-Boc-glycine
  • carbotertbutoxyglycine
  • t-BOC-Gly
  • t-Boc-glycine
  • t-Butoxycarbonylglycine
  • t-butyloxycarbonylglycine
  • tert-Butyloxycarbonylglycine

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