C22H24BrFN4O2
475.4 g/mol
APIDanger
Vandetanib
CAS443913-73-3
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Vandetanib is a quinazoline derivative with methoxy, bromo-fluorophenylamino, and piperidinylmethoxy substituents. It functions as an antineoplastic agent and tyrosine kinase inhibitor, primarily employed as an active pharmaceutical ingredient in targeted cancer therapy.
antineoplastic agenttyrosine kinase inhibitorpharmaceutical manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 443913-73-3
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Safety Reference
Danger
H302Harmful if swallowed
H360May damage fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
InChIKey
UHTHHESEBZOYNR-UHFFFAOYSA-N
SMILES
CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC
Synonyms (24)
- V-9402
- Vandetanib (JAN/USAN/INN)
- 2ivu
- Caprelsa
- Caprelsa (TN)
- VANDETANIB [MART.]
- Vandetanib
- Vandetanib (Standard)
- Vandetanib (Zactima)
- Vandetanib - Bio-X trade mark
- Zactima
- vandetanib (zd6474)
- vandetanibum