C19H20Br2N6O4S
588.3 g/mol
APIDanger
Macitentan
CAS441798-33-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Macitentan is an active pharmaceutical ingredient that functions as an endothelin receptor antagonist. It is a tissue-targeting compound developed for use in pharmaceutical manufacturing and research.
pharmaceutical raw material for research and developmentlaboratory reagent for endothelin receptor studies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongStructure SimilarSimilarity 0.88
Sulfamide, N-[6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-5-(4-chlorophenyl)-4-pyrimidinyl]-N'-propyl-
CAS441798-36-3
pharmaceutical raw material
StrongStructure SimilarSimilarity 0.88
N-[5-(4-Bromophenyl)-6-[2-[(5-chloro-2-pyrimidinyl)oxy]ethoxy]-4- pyrimidinyl]-N'-propylsulfamide
CAS2443747-63-3
pharmaceutical intermediate
SimilarStructure SimilarSimilarity 0.78
Macitentan metabolite M4
CAS1393813-43-8
pharmaceutical raw material
ReferenceSame Category
Diethylamine salicylate
CAS4419-92-5
pharmaceutical raw material
ReferenceSame Category
Harmine
CAS442-51-3
pharmaceutical raw material
ReferenceSame Category
Remogliflozin etabonate
CAS442201-24-3
pharmaceutical raw material
ReferenceSame Category
Foscarnet
CAS4428-95-9
pharmaceutical raw material
Referencesame scaffold
Aprocitentan
CAS1103522-45-7
pharmaceutical raw material
Safety Reference
Danger
H360May damage fertility or the unborn child
Customs Tariff Classification
The international HS code for Macitentan (CAS 441798-33-0) is 2933.59.
HS code (international, 6-digit)
2933.59
EU CN code (8-digit)
2933 59 95
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine
InChIKey
JGCMEBMXRHSZKX-UHFFFAOYSA-N
SMILES
CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br
Synonyms (21)
- Macitentan (JAN/USAN)
- ACT 064992; ACT-064992
- Macitentan
- Macitentan (Standard)
- Macitentan - Bio-X trade mark
- OPSYNVI COMPONENT MACITENTAN
- Opsumit
- Opsumit (TN)
- macitentanum
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