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Home/Compounds/Pharmaceutical Intermediate/O-tert-butyl-L-threonine
C8H17NO3
175.23 g/mol
Pharmaceutical IntermediateWarning

(2S,3R)-2-Amino-3-(tert-butoxy)butanoic acid

CAS4378-13-6EC610-143-6
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is an O-tert-butyl protected threonine derivative, commonly used as a pharmaceutical intermediate. It features an amino acid backbone with a tert-butyl ether protecting group on the hydroxyl side chain, making it valuable in peptide synthesis and pharmaceutical manufacturing.

Pharmaceutical intermediate for peptide synthesisBuilding block for protected amino acid derivatives

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

(2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoic acid

InChIKey

NMJINEMBBQVPGY-RITPCOANSA-N

SMILES

C[C@H]([C@@H](C(=O)O)N)OC(C)(C)C

Synonyms (15)
  • H-Thr(tBu)-OH
  • Linaclotide Impurity 25
  • O-t-Butyl-L-threonine
  • O-tert-Butyl-L-allo-threonine
  • O-tert-Butyl-L-threonine
  • O-tert.-Butylthreonin
  • Threonine tert-butyl ether