C19H17N6NaO6S2
512.5 g/mol
APIDanger
Cefamandole nafate
CAS42540-40-9EC255-877-4
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Cefamandole nafate is a cephalosporin prodrug antibacterial compound, featuring (R)-O-formylmandelamido and N-methylthiotetrazole side-groups. It serves as a prodrug that is converted to its active form in the body to exert antibacterial activity.
Antibacterial prodrug for pharmaceutical manufacturingRaw material for cephalosporin-based drug products
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 42540-40-9
Related Compounds
ReferenceSame Category
Fluorometholone
CAS426-13-1
pharmaceutical raw material
ReferenceSame Category
Ru-25008
CAS426-17-5
pharmaceutical raw material
ReferenceSame Category
Α-cyclopentylmandelic acid
CAS427-49-6
pharmaceutical raw material
ReferenceSame Category
Cyproterone acetate
CAS427-51-0
pharmaceutical raw material
Referencestereoisomer of
O-formylcefamandole
CAS57268-80-1
pharmaceutical raw material
Referencesame scaffold
Cefonicid sodium
CAS61270-78-8
pharmaceutical raw material
Referencesame scaffold
CEFONICID SODIUM
CAS190181-58-9
pharmaceutical raw material
Safety Reference
Danger
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
Identifiers
IUPAC Name
sodium (6R,7R)-7-[[(2R)-2-formyloxy-2-phenylacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
InChIKey
ICZOIXFFVKYXOM-YCLOEFEOSA-M
SMILES
CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)[C@@H](C4=CC=CC=C4)OC=O)SC2)C(=O)[O-].[Na+]
Synonyms (38)
- Cefamandole nafate (USP)
- Bergacef
- CEFAMANDOLE NAFATE [MART.]
- Cedol
- Cefam
- Cefamandol nafato
- Cefamandol nafato [Spanish]
- Cefamandole Nafate sodium
- Cefamandole nafate CRS
- Cefaseptolo
- Cemandil Sodium
- Cephamandole nafate
- Kefadol
- Kefandol
- Lampomandol
- Lilly 106223
- Mandokef
- Mandol
- Mandol (TN)
- Mandolsan
- Neocefal
- O-Formylcefamandole sodium
- Pavecef
- Sodium O-formylcefamandole
- cefamandole nafate
- cemandil sodium salt