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Home/Compounds/API/Piperaquine
C29H32Cl2N6
535.5 g/mol
API

Piperaquine

CAS4085-31-8
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Piperaquine is an aminoquinoline compound consisting of a 1,3-di(piperazin-1-yl)propane core with 7-chloroquinolin-4-yl groups attached to each piperazine nitrogen. It is primarily recognized as an antimalarial active pharmaceutical ingredient.

antimalarial pharmaceutical raw materialintermediate for antimalarial drug manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 1.00

1,4-Bis(3-(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propyl)piperazine

CAS86486-21-7

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.90

Chloropropylquinolinyl piperazine

CAS4038-99-7

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.86

Desarylpiperaquine

CAS4039-00-3

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.80

7-Chloro-4-(4-(3-((7-chloroquinolin-4-yl)oxy)propyl)piperazin-1-yl)quinoline

CAS1233345-93-1

pharmaceutical intermediate

ApplicationSame Use

Cletoquine

CAS4298-15-1

pharmaceutical raw material

ApplicationSame Use

Quinine bisulfate

CAS549-56-4

pharmaceutical raw material

ApplicationSame Use

Quinine hydrochloride dihydrate

CAS6119-47-7

pharmaceutical raw material

ApplicationSame Use

Quinine sulfate dihydrate

CAS6119-70-6

pharmaceutical raw material

Customs Tariff Classification

The international HS code for Piperaquine (CAS 4085-31-8) is 2933.59.

HS code (international, 6-digit)

2933.59

EU CN code (8-digit)

2933 59 95

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

7-chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline

InChIKey

UCRHFBCYFMIWHC-UHFFFAOYSA-N

SMILES

C1CN(CCN1CCCN2CCN(CC2)C3=C4C=CC(=CC4=NC=C3)Cl)C5=C6C=CC(=CC6=NC=C5)Cl

Synonyms (13)
  • Piperaquine (USAN)
  • Piperaquinoline
  • piperaquine
  • piperaquine-phosphate

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