C19H22Cl2FN3O3
430.3 g/mol
APIWarning
Besifloxacin hydrochloride
CAS405165-61-9
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Besifloxacin hydrochloride is the hydrochloride salt of besifloxacin, a synthetic fourth-generation fluoroquinolone antibiotic. It acts by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and cell division, resulting in broad-spectrum antibacterial activity.
antibiotic active pharmaceutical ingredientpharmaceutical raw material for ophthalmic formulations
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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StrongStructure SimilarSimilarity 0.88
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid;hydrochloride
InChIKey
PMQBICKXAAKXAY-HNCPQSOCSA-N
SMILES
C1CCN(C[C@@H](C1)N)C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4CC4)F.Cl
Synonyms (19)
- Besifloxacin hydrochloride (USAN)
- 405165-61-9 (HCl)
- BOL 303224a
- Besifloxacin HCl
- Besifloxacin HCl (Besivance)
- Besifloxacin hydrochloride
- Besivance
- Besivance (TN)
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