C19H21N7O6
443.4 g/mol
Research ReagentWarning
Dihydrofolic acid
CAS4033-27-6EC609-824-0
Category
Research Reagent
Compound Class
Heterocycle
Primary Use
Research Compound
Dihydrofolic acid (DHF) is a derivative of folic acid (vitamin B9) that serves as a substrate in folate metabolism. It is converted to tetrahydrofolic acid by the enzyme dihydrofolate reductase, a step essential for the synthesis of purines and pyrimidines, the building blocks of DNA and RNA.
research compound for folate metabolism studiessubstrate for dihydrofolate reductase assaysreagent in nucleic acid synthesis research
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 4033-27-6
Related Compounds
ReferenceSame Category
2-Amino-2-methylpent-4-ynoic acid
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Referencesame scaffold
10-formyldihydrofolate(2-)
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
InChIKey
OZRNSSUDZOLUSN-LBPRGKRZSA-N
SMILES
C1C(=NC2=C(N1)N=C(NC2=O)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Synonyms (30)
- Calcium Levofolinate EP Impurity G(Dihydrofolic Acid); Calcium Folinate EP Impurity G
- Calcium folinate hydrate Impurity G [EP Impurity]
- Calcium levofolinate hydrate Impurity G [EP Impurity]
- 7,8-Dihydro-L-folic acid
- 7,8-Dihydrofolic acid
- 7,8-Dihydropteroylglutamate
- CALCIUM FOLINATE IMPURITY G
- Dihydrofolic acid
- H2PteGlu
- H2PteGlu1
- dihydrofolate