C22H23ClN2O8
478.9 g/mol
APIWarning
METHACYCLINE HYDROCHLORIDE
CAS3963-95-9EC223-568-3
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material
Methacycline hydrochloride is a tetracycline antibiotic compound primarily used as an active pharmaceutical ingredient in the manufacturing of antibiotic medications. It also serves as a precursor in the industrial synthesis of doxycycline hyclate.
active pharmaceutical ingredient in tetracycline antibiotic productionprecursor for doxycycline hyclate synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Restricted or banned substances
Substances on this list are banned or restricted under the named regulation. This page is a compliance reference — verify your obligations under applicable law.
Relevant lists:California Proposition 65
CAS 3963-95-9
Related Compounds
ReferenceSame Category
Fluticasone furoate
CAS397864-44-7
pharmaceutical raw material
ReferenceSame Category
Amikacin sulfate
CAS39831-55-5
pharmaceutical raw material
ReferenceSame Category
Etizolam
CAS40054-69-1
pharmaceutical raw material
ReferenceSame Category
Vasoactive intestinal octacosapeptide (swine)
CAS40077-57-4
pharmaceutical raw material
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Regulatory Compliance1
- California Proposition 65USRegulation
Customs Tariff Classification
The international HS code for METHACYCLINE HYDROCHLORIDE (CAS 3963-95-9) is 2941.30.
HS code (international, 6-digit)
2941.30
EU CN code (8-digit)
2941 30 00
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
(4S,4aR,5S,5aR,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
InChIKey
VXPSARQTYDZXAO-CCHMMTNSSA-N
SMILES
CN(C)[C@H]1[C@@H]2[C@H]([C@@H]3C(=C)C4=C(C(=CC=C4)O)C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O.Cl
Synonyms (51)
- Doxycycline EP Impurity BHCl
- METHACYCLINE HYDROCHLORIDE (USP MONOGRAPH)
- METHACYCLINE HYDROCHLORIDE (USP-RS)
- Methacycline hydrochloride (JAN/USP)
- Methacycline hydrochloride (USP)
- Methacycline hydrochloride, United States Pharmacopeia (USP)
- 6-Methylene-5-oxytetracycline
- 6-Methyleneoxytetracycline
- Adriamicina
- Ciclobiotic
- Germiciclin
- Globociclina
- Londomycin
- METHACYCLINE HYDROCHLORIDE
- Megamycine
- Metacyclin hydrochloride
- Metacycline HCl
- Metacycline hydrochloride
- Metacycline hydrochloride RS
- Metadomus
- Methacycline HCl
- Metilenbiotic
- Optimycin
- Physiomycine
- Rindex
- Rondomycin
- Rondomycin (TN)