C7H5F3N2O2
206.12 g/mol
Pharmaceutical IntermediateDanger
4-Nitro-3-(trifluoromethyl)aniline
CAS393-11-3EC206-884-6
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate
4-Nitro-3-(trifluoromethyl)aniline is a chemical compound that serves as a major metabolite of flutamide, an antiandrogen medication. It is used primarily as a pharmaceutical intermediate in research and manufacturing settings.
major metabolite of flutamidepharmaceutical intermediate
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
ReferenceSame Category
4-methoxy-3-(trifluoromethyl)aniline
CAS393-15-7
pharmaceutical intermediate
ReferenceSame Category
5-Bromo-2-fluorobenzotrifluoride
CAS393-37-3
pharmaceutical intermediate
ReferenceSame Category
2-Amino-5-fluorobenzotrifluoride
CAS393-39-5
pharmaceutical intermediate
ReferenceSame Category
2-fluorobenzoyl chloride
CAS393-52-2
pharmaceutical intermediate
Safety Reference
Danger
H301Toxic if swallowed
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for 4-Nitro-3-(trifluoromethyl)aniline (CAS 393-11-3) is 2921.43.
HS code (international, 6-digit)
2921.43
EU CN code (8-digit)
2921 43 00
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
4-nitro-3-(trifluoromethyl)aniline
InChIKey
UTKUVRNVYFTEHF-UHFFFAOYSA-N
SMILES
C1=CC(=C(C=C1N)C(F)(F)F)[N+](=O)[O-]
Synonyms (22)
- Flutamide EP Impurity A
- Flutamide EP Impurity A; Nilutamide EP Impurity B
- Flutamide Imp. A (EP); Flutamide USP Related Compound A; Flutamide USP RC A; 4-Nitro-3-(trifluoromethyl)aniline; Flutamide Related Compound A; Flutamide Impurity A
- Nilutamide impurity B, European Pharmacopoeia (EP)
- 3-TFM-4-NA
- FLUTAMIDE IMPURITY A
- NILUTAMIDE IMPURITY B
- Nilutamide impurity B CRS
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