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Home/Compounds/API/Lapatinib ditosylate hydrate
C43H44ClFN4O11S3
943.5 g/mol
APIDanger

Tyverb

CAS388082-78-8
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Tyverb is an active pharmaceutical ingredient that is the ditosylate monohydrate salt form of lapatinib, a member of the quinazoline class of compounds.

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Lapatinib

CAS231277-92-2

pharmaceutical raw material

StrongSame Parent

Lapatinib ditosylate

CAS388082-77-7

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.82

Deschloro Lapatinib

CAS633370-23-7

pharmaceutical raw material

ReferenceSame Category

(S)-(−)-carbidopa monohydrate

CAS38821-49-7

pharmaceutical raw material

ReferenceSame Category

(+)-1-phenethylamine

CAS3886-69-9

pharmaceutical raw material

ReferenceSame Category

Sodium N-sulfoglucosamine

CAS38899-05-7

pharmaceutical raw material

ReferenceSame Category

Nalidixic acid

CAS389-08-2

pharmaceutical raw material

Referencesame scaffold

5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde

CAS231278-84-5

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Danger
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H372Causes damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life

Customs Tariff Classification

The international HS code for Tyverb (CAS 388082-78-8) is 2934.99.

HS code (international, 6-digit)

2934.99

EU CN code (8-digit)

2934 99 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine;bis(4-methylbenzenesulfonic acid);hydrate

InChIKey

XNRVGTHNYCNCFF-UHFFFAOYSA-N

SMILES

CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl.O

Synonyms (27)
  • Lapatinib ditosylate (USAN)
  • 388082-78-8(ditosylate salt)
  • LAPATINIB TOSILATE [MART.]
  • Lapatinib Ditosylate
  • Lapatinib ditosylate hydrate
  • Lapatinib tosilate hydrate
  • Tycerb
  • Tykerb
  • Tykerb (TN)
  • Tyverb
  • Tyverb (TN)
  • lapatinib tosilate

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