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Home/Compounds/Pharmaceutical Intermediate/4-Chloro-6-trifluoromethylpyrimidine
C5H2ClF3N2
182.53 g/mol
Pharmaceutical IntermediateWarning

4-chloro-6-(trifluoromethyl)pyrimidine

CAS37552-81-1EC817-202-7
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

4-chloro-6-(trifluoromethyl)pyrimidine is a fluorinated pyrimidine derivative used as a pharmaceutical intermediate in the manufacturing of tyrosine kinase inhibitors. These inhibitors are a key class of compounds in research and drug development for certain leukemias.

pharmaceutical intermediate for tyrosine kinase inhibitor synthesisresearch compound in kinase inhibitor development

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 37552-81-1

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Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
Identifiers
IUPAC Name

4-chloro-6-(trifluoromethyl)pyrimidine

InChIKey

TYSPDLZOMUDHQZ-UHFFFAOYSA-N

SMILES

C1=C(N=CN=C1Cl)C(F)(F)F

Synonyms (3)

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