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Home/Compounds/Pharmaceutical Intermediate/1,3,5-trifluorobenzene
C6H3F3
132.08 g/mol
Pharmaceutical IntermediateDanger

1,3,5-TRIFLUOROBENZENE

CAS372-38-3EC206-751-2
Category
Pharmaceutical Intermediate
Compound Class
Aromatic
Primary Use
Pharmaceutical Intermediate

1,3,5-Trifluorobenzene is a fluorinated aromatic compound where three hydrogen atoms on the benzene ring are replaced by fluorine atoms at the 1, 3, and 5 positions. It is commonly used as a pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients and other fine chemicals.

Pharmaceutical intermediateBuilding block in organic synthesisReagent for fluorinated chemical research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

3,5-Difluoroaniline

CAS372-39-4

pharmaceutical intermediate

ReferenceSame Category

Methyl 4-hydroxy-6-oxo-1,6-dihydropyridazine-3-carboxylate

CAS372118-00-8

pharmaceutical intermediate

ReferenceSame Category

Methyl 4,6-dichloropyridazine-3-carboxylate

CAS372118-01-9

pharmaceutical intermediate

ReferenceSame Category

2-Aminomethylpyrimidine hydrochloride

CAS372118-67-7

pharmaceutical intermediate

Safety Reference

Flammable
Flammable
Harmful
Harmful
Danger
H225Highly flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for 1,3,5-TRIFLUOROBENZENE (CAS 372-38-3) is 2903.99.

HS code (international, 6-digit)

2903.99

EU CN code (8-digit)

2903 99 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

1,3,5-trifluorobenzene

InChIKey

JXUKFFRPLNTYIV-UHFFFAOYSA-N

SMILES

C1=C(C=C(C=C1F)F)F

Synonyms (6)
  • 1,3,5-TRIFLUOROBENZENE
  • 1,3,5-trifluorbenzol
  • 1,5-Trifluorobenzene
  • Benzene, 1,3,5-trifluoro-
  • Benzene,3,5-trifluoro-
  • sym-Trifluorobenzene

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