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Home/Compounds/Pharmaceutical Intermediate/1-(tert-Butoxycarbonyl)-4-oxo-D-proline
C10H15NO5
229.23 g/mol
Pharmaceutical IntermediateWarning

(2R)-1-[(tert-butoxy)carbonyl]-4-oxopyrrolidine-2-carboxylic acid

CAS364077-84-9EC891-621-3
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate

This compound is a Boc-protected derivative of 4-oxoproline, featuring a pyrrolidine ring with a ketone and carboxylic acid group. It is primarily used as a chiral intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and manufacturing.

Chiral building block for peptide and small-molecule synthesisIntermediate in the production of research-grade bioactive compounds

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 364077-84-9

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Related Compounds

SimilarStructure SimilarSimilarity 0.76

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Referencestereoisomer of

N-Boc-4-oxo-L-proline

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Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

(2R)-1-[(2-methylpropan-2-yl)oxycarbonyl]-4-oxopyrrolidine-2-carboxylic acid

InChIKey

CKYGSXRXTIKGAJ-SSDOTTSWSA-N

SMILES

CC(C)(C)OC(=O)N1CC(=O)C[C@@H]1C(=O)O

Synonyms (11)
  • (2R)-N-Boc-4-oxo-proline
  • Ledipasvir Impurity 33
  • N-Boc-4-Oxo-D-proline