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Home/Compounds/Pharmaceutical Intermediate/5-Chlorothiophene-3-carboxylic acid
C5H3ClO2S
162.59 g/mol
Pharmaceutical IntermediateWarning

5-chlorothiophene-3-carboxylic acid

CAS36157-42-3EC872-943-3
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate

5-Chlorothiophene-3-carboxylic acid is an organic compound featuring a thiophene ring substituted with a chlorine atom and a carboxylic acid group. It serves as a pharmaceutical intermediate used in the manufacturing process of Avatrombopag, a medication for thrombocytopenia associated with chronic liver disease.

Pharmaceutical intermediate for Avatrombopag synthesisLaboratory reagent for research on thrombocytopenia therapies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

Trans-4-Hydroxycyclohexanecarboxylic acid ethyl ester

CAS3618-04-0

pharmaceutical intermediate

ReferenceSame Category

2-Chloro-6-(methanesulfonyl)-1,3-benzothiazole

CAS3622-29-5

pharmaceutical intermediate

ReferenceSame Category

Benzothiazole-6-carboxylic acid

CAS3622-35-3

pharmaceutical intermediate

ReferenceSame Category

Ethyl malonyl chloride

CAS36239-09-5

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

5-chlorothiophene-3-carboxylic acid

InChIKey

POVPYUUZOZBLOH-UHFFFAOYSA-N

SMILES

C1=C(SC=C1C(=O)O)Cl

Synonyms (6)
  • 9E6
  • Rivaroxaban Impurity 24

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