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Home/Compounds/Pharmaceutical Intermediate/Boc-L-Histidine(Tosyl)
C18H23N3O6S
409.5 g/mol
Pharmaceutical Intermediate

Boc-His(Tos)-OH

CAS35899-43-5
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

Boc-His(Tos)-OH is a protected histidine derivative used in solid-phase peptide synthesis. The compound features a tert-butoxycarbonyl (Boc) protecting group on the alpha-amino group and a tosyl (Tos) group on the imidazole side chain, enabling selective deprotection during peptide assembly.

Protected building block for peptide synthesisIntermediate for pharmaceutical research and manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Referencesame scaffold

1-(p-Toluenesulfonyl)imidazole

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research compound

Identifiers
IUPAC Name

(2S)-3-[1-(4-methylphenyl)sulfonylimidazol-4-yl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

InChIKey

DCLJSEPKYJSEHW-HNNXBMFYSA-N

SMILES

CC1=CC=C(C=C1)S(=O)(=O)N2C=C(N=C2)C[C@@H](C(=O)O)NC(=O)OC(C)(C)C

Synonyms (16)
  • (R)-L-(+)-Boc-his(tos)-OH
  • Boc-His(1-Tos)-OH
  • Boc-His(Tos)-OH
  • Boc-His-(Tos)
  • Boc-L-His(Tos)-OH
  • N-Boc-1-tosyl-L-histidine