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Home/Compounds/Pharmaceutical Intermediate/2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid
C11H8F6O4
318.17 g/mol
Pharmaceutical IntermediateWarning

2,5-bis(2,2,2-trifluoroethoxy)benzoic Acid

CAS35480-52-5EC609-132-9
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate

2,5-bis(2,2,2-trifluoroethoxy)benzoic acid is a chemical compound used as a pharmaceutical intermediate in the synthesis of flecainide. It features a benzoic acid core with two trifluoroethoxy substituents, contributing to its role in pharmaceutical manufacturing.

pharmaceutical intermediate for flecainide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.75

1-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]ethan-1-one

CAS76784-40-2

intermediate for agrochemical or pharmaceutical synthesis

SimilarStructure SimilarSimilarity 0.73

2,2,2-trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate

CAS50778-57-9

research compound

ReferenceSame Category

Methyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide

CAS35511-15-0

pharmaceutical intermediate

ReferenceSame Category

2-Propenoic acid, 2-(phosphonooxy)-, cyclohexanamine (1:3)

CAS35556-70-8

pharmaceutical intermediate

ReferenceSame Category

Methylglucamine hydrochloride

CAS35564-86-4

pharmaceutical intermediate

ReferenceSame Category

3-Chloro-1,1-diethoxypropane

CAS35573-93-4

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

2,5-bis(2,2,2-trifluoroethoxy)benzoic acid

InChIKey

YPGYLCZBZKRYQJ-UHFFFAOYSA-N

SMILES

C1=CC(=C(C=C1OCC(F)(F)F)C(=O)O)OCC(F)(F)F

Synonyms (14)
  • FLECAINIDE ACID (USP IMPURITY)
  • Flecainide Acetate EP Impurity D
  • Flecainide Acetate Imp. D (EP); 2,5-Bis(2,2,2-trifluoroethoxy)benzoic Acid; Flecainide Acetate Impurity D; Flecainide Impurity D
  • Flecainide EP Impurity D
  • FLECAINIDE ACID
  • Flecainide IMpurity D
  • Flecainide acetate impurity D