C4H10O2S2
154.3 g/mol
Research ReagentDanger
Dithiothreitol
CAS3483-12-3EC222-468-7
Category
Research Reagent
Compound Class
Other
Primary Use
Research Compound
Dithiothreitol (DTT) is a colorless organosulfur compound commonly used as a reducing agent for disulfide bonds in biochemical research. It is a dithiol and diol, also known as Cleland's reagent.
Biochemical reducing agent for disulfide bondsLaboratory reagent for protein and peptide research
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 3483-12-3
Related Compounds
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Referencestereoisomer of
Dithioerythritol
CAS6892-68-8
research compound
Referencestereoisomer of
1,4-Bis[(²H)sulfanyl](²H₆)butane-2,3-(²H₂)diol
CAS302912-05-6
research compound
Safety Reference
Danger
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
H412Harmful to aquatic life with long lasting effects
H312Harmful in contact with skin
Identifiers
IUPAC Name
(2R,3R)-1,4-bis(sulfanyl)butane-2,3-diol
InChIKey
VHJLVAABSRFDPM-IMJSIDKUSA-N
SMILES
C([C@@H]([C@H](CS)O)O)S
Synonyms (46)
- DTT
- 1,4-Dithio-dl-threitol
- 1,4-Dithiothreitol
- CLELAND REAGENT RACEMIC
- Cleland reagent
- Cleland's reagent
- Dithiothreitol
- Dithiotreitol
- L-1,4-Dithiothreitol
- L-Cleland's Reagent
- L-Dithiothreitol
- L-Dtt
- Mucolyse
- Reagent, Cleland
- Reagent, Cleland's
- Sputolysin
- Threitol, 1,4-dithio-
- Threitol, 1,4-dithio-, DL-
- Threitol, dithio-
- WR 34678
- dl-Dithiothreitol
- rac-Dithiothreitol