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Home/Compounds/Pharmaceutical Intermediate/N-Cbz-L-proline N-hydroxysuccinimide ester
C17H18N2O6
346.3 g/mol
Pharmaceutical Intermediate

1,2-Pyrrolidinedicarboxylic acid, 2-(2,5-dioxo-1-pyrrolidinyl) 1-(phenylmethyl) ester, (2S)-

CAS3397-33-9
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

N-Benzoxycarbonyl-L-proline succinimido ester is a protected amino acid derivative used as a coupling reagent in peptide synthesis. Its structure contains a succinimidyl ester group that facilitates amide bond formation while the benzyloxycarbonyl (Cbz) group protects the amino function.

Protected amino acid coupling reagent in peptide synthesisIntermediate for pharmaceutical manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

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Identifiers
IUPAC Name

1-O-benzyl 2-O-(2,5-dioxopyrrolidin-1-yl) (2S)-pyrrolidine-1,2-dicarboxylate

InChIKey

BDNYCEKWUBRCBJ-ZDUSSCGKSA-N

SMILES

C1C[C@H](N(C1)C(=O)OCC2=CC=CC=C2)C(=O)ON3C(=O)CCC3=O

Synonyms (9)
  • Z-L-Pro-OSu
  • Z-Pro-OSu