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Home/Compounds/API/Lubiprostone
C20H32F2O5
390.5 g/mol
API

Lubiprostone

CAS333963-40-9EC603-977-7
Category
API
Compound Class
Organic Acid
Primary Use
Pharmaceutical Raw Material

Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that activates ClC-2 chloride channels on gastrointestinal epithelial cells, promoting chloride-rich fluid secretion. It is used in the management of idiopathic chronic constipation and irritable bowel syndrome.

Pharmaceutical raw material for chloride channel activator formulationsCompound used in manufacturing of constipation management products

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

Methyl 4-[(piperidin-4-yl)methyl]benzoate hydrochloride

CAS333986-70-2

pharmaceutical raw material

ReferenceSame Category

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CAS33401-94-4

pharmaceutical raw material

ReferenceSame Category

Etoposide

CAS33419-42-0

antineoplastic chemotherapeutic agent

ReferenceSame Category

Trimagnesium dicitrate

CAS3344-18-1

pharmaceutical raw material

Customs Tariff Classification

The international HS code for Lubiprostone (CAS 333963-40-9) is 2937.50.

HS code (international, 6-digit)

2937.50

EU CN code (8-digit)

2937 50 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid

InChIKey

WGFOBBZOWHGYQH-MXHNKVEKSA-N

SMILES

CCCCC([C@]1(CC[C@H]2[C@H](O1)CC(=O)[C@@H]2CCCCCCC(=O)O)O)(F)F

Synonyms (29)
  • Lubiprostone (JAN/USAN/INN)
  • 0211, RU
  • 0211, SPI
  • 333963-40-9 (hemiketal)
  • Amitiza
  • Amitiza (TN)
  • Amitza
  • Bicyclic lubiprostone
  • CAS# 333963-40-9
  • LUBIPROSTONE [MART.]
  • Lubiprostone
  • Lubiprostone (ring open)
  • Lubiprostone hemiketal
  • Lubiprostone powder
  • lubiprostona
  • lubiprostonum

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