C29H36O10
544.6 g/mol
Pharmaceutical IntermediateDanger
10-Deacetylbaccatin III
CAS32981-86-5
Category
Pharmaceutical Intermediate
Compound Class
Natural Product
Primary Use
Pharmaceutical Intermediate
10-Deacetylbaccatin III is a natural organic compound isolated from the yew tree. It serves as a key precursor in the manufacturing of the pharmaceutical intermediate used to produce the anti-cancer drug docetaxel (Taxotere).
Precursor in anti-cancer drug docetaxel manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Sourcing or supplying this compound?
List your inventory or post a purchase request
CAS 32981-86-5
Related Compounds
StrongStructure SimilarSimilarity 0.86
Baccatin III
CAS27548-93-2
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.74
7,10-Dimethoxy-10-DAB III
CAS183133-94-0
pharmaceutical intermediate
ReferenceSame Category
(1S)-2-chloro-1-(2,4-difluorophenyl)ethanol
CAS330156-49-5
pharmaceutical intermediate
ReferenceSame Category
(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
CAS330156-50-8
pharmaceutical intermediate
ReferenceSame Category
1-Tritylimidazole-4-carboxaldehyde
CAS33016-47-6
pharmaceutical intermediate
ReferenceSame Category
2-Chloro-4-(trifluoromethyl)pyrimidine
CAS33034-67-2
pharmaceutical intermediate
Safety Reference
Danger
H301Toxic if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H373May cause damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects
Identifiers
IUPAC Name
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12,15-tetrahydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
InChIKey
YWLXLRUDGLRYDR-ZHPRIASZSA-N
SMILES
CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O
Synonyms (26)
- 10-DAB
- Docetaxel EP Impurity E
- 10-DAB (10-Deacetylbaccatin)
- 10-DB III
- 10-Deacetyl Baccatin lll
- 10-Deacetylbaccatin
- 10-Deacetylbaccatin III
- 10-Deacetylbaccatine III
- 10-O-Deacetylbaccatin III
- 10-deactyl baccatin III
- 10.BETA.-DEACETYLBACCATIN III
- Baccatin III, 10-Deacetyl-
- Docetaxel impurity E CRS
- zoate