C18H42O6Si4
466.9 g/mol
Pharmaceutical IntermediateWarning
2,3,4,6-tetrakis-o-trimethylsilyl-d-gluconolactone
CAS32384-65-9EC608-732-8
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate
This compound is a pertrimethylsilylated derivative of glucono-1,5-lactone, serving as a protected intermediate in the synthesis of the pharmaceutical agent empagliflozin.
Pharmaceutical intermediate for empagliflozin manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 32384-65-9
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Referencesame scaffold
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Safety Reference
Warning
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H411Toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
(3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-(trimethylsilyloxymethyl)oxan-2-one
InChIKey
VNGTZLYNGGLPIZ-WCXIOVBPSA-N
SMILES
C[Si](C)(C)OC[C@@H]1[C@H]([C@@H]([C@H](C(=O)O1)O[Si](C)(C)C)O[Si](C)(C)C)O[Si](C)(C)C
Synonyms (14)
- Canagliflozin Impurity 34