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Home/Compounds/Pharmaceutical Intermediate/N-(3-Chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4-quinazolinamine
C18H14ClFN4O4
404.8 g/mol
Pharmaceutical Intermediate

N-(3-Chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4-quinazolinamine

CAS314771-88-5
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a quinazolinamine derivative with a stereocenter, featuring nitro, ether, and halogen substituents. It serves as a pharmaceutical intermediate, primarily used in research and manufacturing contexts.

pharmaceutical intermediate

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.73

(S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)formamide (Afatinib Impurity)

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2-Ethoxy-5-nitropyridine

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Referencestereoisomer of

(R)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine

CAS402855-07-6

pharmaceutical intermediate

Identifiers
IUPAC Name

N-(3-chloro-4-fluorophenyl)-6-nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-4-amine

InChIKey

UXAZURVGMXJLSO-NSHDSACASA-N

SMILES

C1COC[C@H]1OC2=C(C=C3C(=C2)N=CN=C3NC4=CC(=C(C=C4)F)Cl)[N+](=O)[O-]

Synonyms (8)
  • Afatinib Impurity A

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