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Home/Compounds/Other/Treosulfan
C6H14O8S2
278.3 g/mol
OtherDanger

Treosulfan

CAS299-75-2EC206-081-0
Category
Other
Compound Class
n.a
Primary Use
Conditioning treatment prior to allogeneic hematopoietic stem cell transplantation

Treosulfan is an alkylating agent used as a conditioning treatment prior to allogeneic hematopoietic stem cell transplantation. It clears the bone marrow to make room for transplanted donor cells, and is administered together with fludarabine in both adults and children from one month of age with blood cancers or other severe disorders requiring a transplant.

Conditioning agent for allogeneic hematopoietic stem cell transplantationUsed in combination with fludarabine in blood cancer patientsUsed as a conditioning treatment for other severe disorders requiring bone marrow transplant

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Research compound

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Safety Reference

Health Hazard
Health Hazard
Danger
H340May cause genetic defects
H350May cause cancer
H371May cause damage to organs
Identifiers
IUPAC Name

[(2S,3S)-2,3-dihydroxy-4-methylsulfonyloxybutyl] methanesulfonate

InChIKey

YCPOZVAOBBQLRI-WDSKDSINSA-N

SMILES

CS(=O)(=O)OC[C@@H]([C@H](COS(=O)(=O)C)O)O

Synonyms (34)
  • Treosulfan (JAN/USAN/INN)
  • Treosulfano [INN-Spanish]
  • Treosulfanum [INN-Latin]
  • Dihydroxybusulfan
  • Dihydroxymyleran
  • Grafapex (TN)
  • L-Threityl dimesylate
  • L-dihydroxybusulfan
  • Ovastat
  • Ovastat (TN)
  • TREOSULFAN [MART.]
  • Trecondi
  • Treosulfan
  • Treosulfano
  • Treosulfanum
  • Treosulphan
  • Tresulfan
  • Tresulfon
  • threosulphan