C10H10N2O4
222.2 g/mol
Pharmaceutical IntermediateWarning
6,7-Dimethoxyquinazoline-2,4(1H,3H)-dione
CAS28888-44-0EC249-288-1
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
This compound is a pharmaceutical intermediate used in the manufacturing of alpha1-adrenergic blockers. It serves as a key intermediate for the production of medications such as alfuzosin, prazosin, terazosin, doxazosin, and IAAP, which are effective as antihypertensives.
Intermediate for alpha1-adrenergic blockersIntermediate for antihypertensive agents
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 28888-44-0
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
6,7-dimethoxy-1H-quinazoline-2,4-dione
InChIKey
KWNQIIMVPSMYEM-UHFFFAOYSA-N
SMILES
COC1=C(C=C2C(=C1)C(=O)NC(=O)N2)OC
Synonyms (21)
- Doxazosin EP Impurity D
- Doxazosin impurity D, European Pharmacopoeia (EP)
- DOXAZOSIN IMPURITY D
- DOXAZOSIN MESILATE IMPURITY D
- Doxazosin impurity D CRS
- Quinazolindi one