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Home/Compounds/Pharmaceutical Intermediate/Tert-butyl 4,4-difluoropiperidine-1-carboxylate
C10H17F2NO2
221.24 g/mol
Pharmaceutical IntermediateWarning

Tert-butyl 4,4-difluoropiperidine-1-carboxylate

CAS281652-10-6EC822-079-8
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

Tert-butyl 4,4-difluoropiperidine-1-carboxylate is a fluorinated piperidine derivative used primarily as a pharmaceutical intermediate in organic synthesis. Its structure features a tert-butyl carbamate protecting group and two geminal fluorine atoms on the piperidine ring, contributing to its utility in building complex molecules.

Pharmaceutical intermediate in drug developmentBuilding block for fluorinated organic compounds

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

(S)-3,3-Difluoro-1-methylpiperidin-4-amine dihydrochloride

CAS2816818-12-7

pharmaceutical intermediate

ReferenceSame Category

Ethyl 3,3-difluoro-4-(4-fluorophenyl)-4-hydroxybutanoate

CAS2816913-87-6

pharmaceutical intermediate

ReferenceSame Category

3-Cyanobenzyl bromide

CAS28188-41-2

pharmaceutical intermediate

ReferenceSame Category

N-(3-acetyl-4-(oxiran-2-ylmethoxy)phenyl)butanamide

CAS28197-66-2

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

tert-butyl 4,4-difluoropiperidine-1-carboxylate

InChIKey

HHBBBPZPEBZLII-UHFFFAOYSA-N

SMILES

CC(C)(C)OC(=O)N1CCC(CC1)(F)F

Synonyms (8)
  • 1-Boc-4,4-difluoropiperidine
  • N-Boc-4,4-Difluoropiperidine

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