C9H8O3
164.16 g/mol
Pharmaceutical IntermediateDanger
Himic anhydride
CAS2746-19-2EC220-384-5
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate
Himic anhydride, also known as nadic anhydride or 5-norbornene-2,3-dicarboxylic anhydride, is an organic acid anhydride derivative of norbornene. It is primarily used as a pharmaceutical intermediate in the synthesis of lurasidone.
Intermediate for lurasidone synthesisBuilding block in organic synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.73
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pharmaceutical intermediate
ReferenceSame Category
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ReferenceSame Category
2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol
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pharmaceutical intermediate
Referencestereoisomer of
Nadic anhydride
CAS826-62-0
pharmaceutical intermediate
Referencestereoisomer of
Carbic anhydride
CAS129-64-6
pharmaceutical intermediate
Safety Reference
Danger
H317May cause an allergic skin reaction
H318Causes serious eye damage
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
Customs Tariff Classification
The international HS code for Himic anhydride (CAS 2746-19-2) is 2917.20.
HS code (international, 6-digit)
2917.20
EU CN code (8-digit)
2917 20 00
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
(1R,2R,6S,7S)-4-oxatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
InChIKey
KNDQHSIWLOJIGP-RNGGSSJXSA-N
SMILES
C1[C@@H]2C=C[C@H]1[C@H]3[C@@H]2C(=O)OC3=O
Synonyms (29)
- EXO-CARBIC ANHYDRIDE
- EXO-NADIC ANHYDRIDE
- Himic anhydride
- Lurasidone Impurity 94
- endicanhydride
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