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Home/Compounds/Pharmaceutical Intermediate/(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carboxylic acid
C15H15F5O4
354.27 g/mol
Pharmaceutical Intermediate

(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carboxylic acid

CAS2649470-87-9
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate

This compound is a chiral pharmaceutical intermediate featuring a tetrahydrofuran ring substituted with a difluoromethoxyphenyl group and multiple fluorine atoms. Its stereochemistry is defined, making it suitable for use in the synthesis of enantiomerically pure active pharmaceutical ingredients.

pharmaceutical intermediate

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carboxylic acid (R)-1-phenylethan-1-amine salt

CAS2649470-89-1

research reagent

ReferenceSame Category

N-Carbobenzyloxy-L-glutamine

CAS2650-64-8

pharmaceutical intermediate

ReferenceSame Category

(S)-(+)-1-Methoxy-2-propanol

CAS26550-55-0

pharmaceutical intermediate

ReferenceSame Category

3-amino-N-(4-aminophenyl)benzamide

CAS2657-93-4

pharmaceutical intermediate

ReferenceSame Category

5-(acetoacetylamino)benzimidazolone

CAS26576-46-5

pharmaceutical intermediate

Referencesame scaffold

(3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-yl acetate

CAS2875066-46-7

pharmaceutical raw material

Referencesame scaffold

Suzetrigine Impurity 4

CAS2875067-17-5

pharmaceutical raw material

Identifiers
IUPAC Name

(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)oxolane-2-carboxylic acid

InChIKey

HMJBDIINGXHMMN-BEWJGFNTSA-N

SMILES

C[C@H]1[C@H]([C@@H](O[C@@]1(C)C(F)(F)F)C(=O)O)C2=C(C(=C(C=C2)F)F)OC

Synonyms (6)
  • Suzetrigine Impurity 1
  • Suzetrigine Impurity 2