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Home/Compounds/API/Lirafugratinib
C28H24FN7O2
509.5 g/mol
API

Lirafugratinib

CAS2549174-42-5
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Lirafugratinib is an orally bioavailable inhibitor of fibroblast growth factor receptor 2 (FGFR2), designed as a pharmaceutical raw material for research and manufacturing applications. It acts by binding to FGFR2 and inhibiting the downstream signal transduction pathways involved in cellular proliferation.

pharmaceutical raw material for FGFR2 inhibitor researchcompound used in antineoplastic drug development studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

Clindamycin palmitate hydrochloride

CAS25507-04-4

pharmaceutical raw material

ReferenceSame Category

Alovudine

CAS25526-93-6

pharmaceutical raw material

ReferenceSame Category

Diflorasone

CAS2557-49-5

pharmaceutical raw material

ReferenceSame Category

Desmethylflunitrazepam

CAS2558-30-7

pharmaceutical raw material

Customs Tariff Classification

The international HS code for Lirafugratinib (CAS 2549174-42-5) is 2933.59.

HS code (international, 6-digit)

2933.59

EU CN code (8-digit)

2933 59 95

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

N-[4-[4-amino-5-[3-fluoro-4-(4-methylpyrimidin-2-yl)oxyphenyl]-7-methylpyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-2-methylprop-2-enamide

InChIKey

XOQVZSSDIQQUGO-UHFFFAOYSA-N

SMILES

CC1=NC(=NC=C1)OC2=C(C=C(C=C2)C3=C(N(C4=NC=NC(=C34)N)C)C5=CC=C(C=C5)NC(=O)C(=C)C)F

Synonyms (15)
  • Lirafugratinib (USAN)
  • FGFR2 Inhibitor RLY-4008
  • FGFR2-IN-3
  • Lirafugratinib
  • Rly 4008
  • US11780845, Example 1028
  • US11780845, Example 343
  • WHO 12482
  • example 343
  • example 343 (WO2020231990A1)

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