C7H4ClNO4
201.56 g/mol
Research ReagentDanger
5-CHLORO-2-NITROBENZOIC ACID
CAS2516-95-2EC219-738-1
Category
Research Reagent
Compound Class
Organic Acid
Primary Use
Research Compound
5-Chloro-2-nitrobenzoic acid is a small-molecule research compound that acts as an antagonist of the sonic hedgehog (Shh) signaling pathway by targeting the smoothened (SMO) receptor. It is used as a tool to study hedgehog-dependent processes in developmental biology and oncology, including aberrant pathway activation associated with certain cancers.
Research reagent for hedgehog pathway studiesTool compound for investigating smoothened receptor antagonismLead compound for targeted anticancer therapeutic development
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Sourcing or supplying this compound?
List your inventory or post a purchase request
CAS 2516-95-2
Related Compounds
SimilarStructure SimilarSimilarity 0.74
4-Chloro-2-nitrobenzoic acid
CAS6280-88-2
pharmaceutical intermediate
ReferenceSame Category
2-Chloro-5-nitrobenzoic acid
CAS2516-96-3
research compound
ReferenceSame Category
2'-O-MOE-rC
CAS251647-54-8
research compound
ReferenceSame Category
(1R)-8-chloro-1-methyl-3-nitroso-2,3,4,5-tetrahydro-1H-3-benzazepine
CAS2518136-84-8
research compound
ReferenceSame Category
(5R,6S)-2-[(4-Chlorophenyl)amino]-5-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-5,6-dihydro-4H-1,3-oxazin-4-one
CAS2518301-34-1
research compound
Safety Reference
Danger
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
H400Very toxic to aquatic life
Identifiers
IUPAC Name
5-chloro-2-nitrobenzoic acid
InChIKey
ZKUYSJHXBFFGPU-UHFFFAOYSA-N
SMILES
C1=CC(=C(C=C1Cl)C(=O)O)[N+](=O)[O-]
Synonyms (6)
- 2-nitro-5-chlorobenzoic acid
- 3-chloro-6-nitrobenzoic acid
- 5-CHLORO-2-NITROBENZOIC ACID
- 5-chloro-2-nitrobenzic acid
- 6-Nitro-3-chlorobenzoic acid