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Home/Compounds/API/(S,E)-N-(4-((4-CHLORO-3-FLUOROPHENYL)AMINO)-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)-4-(DIMETHYLAMINO)BUT-2-ENAMIDE
C24H25ClFN5O3
485.9 g/mol
API

(S,E)-N-(4-((4-CHLORO-3-FLUOROPHENYL)AMINO)-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)-4-(DIMETHYLAMINO)BUT-2-ENAMIDE

CAS2475094-87-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

This compound is an active pharmaceutical ingredient used in pharmaceutical manufacturing. It is a quinazoline derivative with a complex structure that includes an amide, amine, and ether functional groups.

Pharmaceutical raw material for manufacturingResearch compound for pharmaceutical studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.88

(S,E)-N-(4-((3,4-Difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide (Afatinib Impurity)

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pharmaceutical raw material

StrongStructure SimilarSimilarity 0.88

(S,E)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide (Afatinib Impurity)

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SimilarStructure SimilarSimilarity 0.83

Afatinib Impurity 18

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SimilarStructure SimilarSimilarity 0.83

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Identifiers
IUPAC Name

(E)-N-[4-(4-chloro-3-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide

InChIKey

CIGJZGGVLAOLAG-CWDCEQMOSA-N

SMILES

CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)Cl)F)O[C@H]4CCOC4

Synonyms (11)
  • 4-Chloro-3-fluoro Afatinib