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Home/Compounds/API/Thyrotropin-releasing hormone
C16H22N6O4
362.38 g/mol
APIWarning

Protirelin

CAS24305-27-9EC246-143-4
Category
API
Compound Class
Peptide
Primary Use
Pharmaceutical Raw Material

Protirelin is a tripeptide composed of L-pyroglutamyl, L-histidyl, and L-prolinamide residues. It functions as a human metabolite and is used as an active pharmaceutical ingredient.

Human metabolitePeptide hormoneActive pharmaceutical ingredient

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.74

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Referencestereoisomer of

Acetic acid;N-[1-(2-carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

CAS120876-23-5

research compound

Safety Reference

Harmful
Harmful
Warning
H332Harmful if inhaled
Identifiers
IUPAC Name

(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

InChIKey

XNSAINXGIQZQOO-SRVKXCTJSA-N

SMILES

C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CCC(=O)N3)C(=O)N

Synonyms (72)
  • TRF
  • TRH
  • TSH-RF
  • PROTIRELIN (EP MONOGRAPH)
  • Protirelin (JP18/USAN/INN)
  • Protirelina [INN-Spanish]
  • Protireline [INN-French]
  • Protirelinum [INN-Latin]
  • 24305-27-9 (free base)
  • 5-oxo-pro-his-pro-nh2
  • Abbott 38579
  • D-His-Protirelin CRS
  • HOLO-TRANSFERRIN
  • Human Transferrin
  • Lopremone
  • PROTIRELIN [MART.]
  • Protirelin Acetate
  • Protirelin CRS
  • Protirelin, synthetic
  • Protirelina
  • Protireline
  • Protirelinum
  • PyroGlu-His-prolinamide
  • Relefact TRH
  • Relefact TRH (TN)
  • Rifathyroin
  • Ro 8-6270/9
  • Stimu-TSH
  • Synthetic TRF
  • Synthetic TRH
  • THYREL TRH
  • TRH, Relefact
  • TSH-releasing factor
  • Thypinone
  • Thyrefact
  • Thyroliberin
  • Thyroliberin TRH Merck
  • Thyrotropic-releasing factor
  • Thyrotropin-releasing factor
  • Trh-cambridge
  • [3H]-TRH
  • [3H]TRH (human, mouse, rat)
  • protirelin
  • trh-sr