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Home/Compounds/Pharmaceutical Intermediate/5'(E)-VP-2'-OMe-A(Bz) Phosphoramidite
C40H57N7O12P2
889.9 g/mol
Pharmaceutical Intermediate

5'(E)-VP-2'-OMe-A(Bz) Phosphoramidite

CAS2419895-65-9
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a phosphoramidite monomer used in oligonucleotide synthesis, characterized by its complex structure including multiple aromatic rings, ester groups, and a nitrile group. It serves as a building block for the assembly of modified oligonucleotides in research and pharmaceutical manufacturing.

Oligonucleotide synthesis phosphoramidite monomerBuilding block for modified oligonucleotides

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

[[(E)-2-[(2R,3R,4R,5R)-5-(6-benzamidopurin-9-yl)-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-methoxyoxolan-2-yl]ethenyl]-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate

InChIKey

DCUPCJOKPAHCLB-OZKJWBRJSA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)/C=C/P(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C

Synonyms (1)

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