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Home/Compounds/Pharmaceutical Intermediate/4-hydroxyindole
C8H7NO
133.15 g/mol
Pharmaceutical IntermediateWarning

4-Hydroxyindole

CAS2380-94-1EC219-177-2
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

4-Hydroxyindole is an indole derivative used as a pharmaceutical intermediate. It serves as a key precursor in the chemical synthesis of psilocybin, a naturally occurring tryptamine alkaloid with serotonergic activity found in certain mushrooms.

Precursor for psilocybin synthesisPharmaceutical intermediate

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

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ReferenceSame Category

(2S,5S)-5-((Benzyloxy)amino)piperidine-2-carboxamide

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pharmaceutical intermediate

ReferenceSame Category

5-Chloro-2-hydroxy-4,6-dimethyl-nicotinonitrile

CAS23819-92-3

pharmaceutical intermediate

ReferenceSame Category

Tert-Butyl (S)-(3,3-difluoropiperidin-4-yl)carbamate

CAS2382503-76-4

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for 4-Hydroxyindole (CAS 2380-94-1) is 2933.99.

HS code (international, 6-digit)

2933.99

EU CN code (8-digit)

2933 99 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

1H-indol-4-ol

InChIKey

NLMQHXUGJIAKTH-UHFFFAOYSA-N

SMILES

C1=CC2=C(C=CN2)C(=C1)O

Synonyms (13)
  • 1H-Indol-4-ol; Pindolol Imp. E (EP); Pindolol Impurity E
  • Pindolol EP Impurity E
  • 1H-Indol-4-ol
  • 1h-indole-4-ol
  • 4- HYDROXYCARBAZOLE
  • 4-Hdroxyindole
  • 4-Hydroxyindole
  • 4-Hydroxyindole (Standard)
  • 4-Indolol
  • 4-hydroxy-1h-indole
  • 4-hydroxyindole, 18
  • PINDOLOL IMPURITY E
  • hydroxyindoles

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