C5H5N5
135.13 g/mol
Research ReagentDanger
1H-Pyrazolo[3,4-d]pyrimidin-4-amine
CAS2380-63-4EC219-174-6
Category
Research Reagent
Compound Class
Heterocycle
Primary Use
Research Compound
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, commonly known as PP2, is a research compound widely used as an inhibitor of Src-family kinases, including Lck, Fyn, and Hck. It has been employed extensively in cancer research, though recent studies indicate it is non-selective and inhibits many other kinases with similar affinities.
Src-family kinase inhibition researchCancer research reagent
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 2380-63-4
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Referencesame scaffold
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Safety Reference
Danger
H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
1H-pyrazolo[3,4-d]pyrimidin-4-amine
InChIKey
LHCPRYRLDOSKHK-UHFFFAOYSA-N
SMILES
C1=NNC2=NC=NC(=C21)N
Synonyms (20)
- TVW
- 4 APP
- 4-Aminopyrazolopyrimidine
- 7-DEAZA-8-AZAADENINE
- 8-Aza-7-deazaadenine
- Pyrazoloadenine