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Home/Compounds/API/Vanzacaftor
C32H39N7O4S
617.8 g/mol
API

Vanzacaftor

CAS2374124-49-7
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Vanzacaftor is a small-molecule compound designed to correct the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. It is used in combination with other CFTR modulators to enhance CFTR quantity and activity at the cell surface.

pharmaceutical raw material for CFTR corrector combinationsactive pharmaceutical ingredient used in manufacturing of cystic fibrosis therapies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

Bexotegras

CAS2376257-44-0

pharmaceutical raw material

ReferenceSame Category

Probenecid sodium

CAS23795-03-1

pharmaceutical raw material

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Retatrutide

CAS2381089-83-2

pharmaceutical raw material

ReferenceSame Category

Ambroxol hydrochloride

CAS23828-92-4

pharmaceutical raw material

Customs Tariff Classification

The international HS code for Vanzacaftor (CAS 2374124-49-7) is 2934.99.

HS code (international, 6-digit)

2934.99

EU CN code (8-digit)

2934 99 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(14S)-8-[3-(2-dispiro[2.0.24.13]heptan-7-ylethoxy)pyrazol-1-yl]-12,12-dimethyl-2,2-dioxo-2lambda6-thia-3,9,11,18,23-pentazatetracyclo[17.3.1.111,14.05,10]tetracosa-1(22),5(10),6,8,19(23),20-hexaen-4-one

InChIKey

VCSUIBJKYCVWNF-NRFANRHFSA-N

SMILES

CC1(C[C@@H]2CCCNC3=NC(=CC=C3)S(=O)(=O)NC(=O)C4=C(N1C2)N=C(C=C4)N5C=CC(=N5)OCCC6C7(C68CC8)CC7)C

Synonyms (16)
  • Vanzacaftor (USAN/INN)
  • US11866450, Compound 195
  • US11866450, Compound 252
  • US11866450, Compound 253
  • US11866450, Compound 274
  • US11866450, Compound 298
  • US11866450, Compound 300
  • US11866450, Compound 301
  • Vanzacaftor

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