C10H10ClN3O2
239.66 g/mol
Pharmaceutical IntermediateWarning
4-Amino-2-chloro-6,7-dimethoxyquinazoline
CAS23680-84-4EC245-821-7
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
4-Amino-2-chloro-6,7-dimethoxyquinazoline is a chemical compound used as a pharmaceutical intermediate. It serves as a key building block in the synthesis of alfuzosin, an alpha-1 blocker medication for benign prostatic hyperplasia.
Pharmaceutical intermediate for alfuzosin synthesisRaw material for alpha-1 blocker manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
ReferenceSame Category
6-Aminoisoquinoline
CAS23687-26-5
pharmaceutical intermediate
ReferenceSame Category
2-Fluoro-3-methylpyridine
CAS2369-18-8
pharmaceutical intermediate
ReferenceSame Category
2-Fluoro-5-methylpyridine
CAS2369-19-9
pharmaceutical intermediate
ReferenceSame Category
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
CAS23735-43-5
pharmaceutical intermediate
Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H373May cause damage to organs through prolonged or repeated exposure
Customs Tariff Classification
The international HS code for 4-Amino-2-chloro-6,7-dimethoxyquinazoline (CAS 23680-84-4) is 2933.59.
HS code (international, 6-digit)
2933.59
EU CN code (8-digit)
2933 59 95
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
2-chloro-6,7-dimethoxyquinazolin-4-amine
InChIKey
HWIIAAVGRHKSOJ-UHFFFAOYSA-N
SMILES
COC1=C(C=C2C(=C1)C(=NC(=N2)Cl)N)OC
Synonyms (27)
- ALFUZOSIN HYDROCHLORIDE IMPURITY B (EP IMPURITY)
- DOXAZOSIN MESILATE IMPURITY F (EP IMPURITY)
- Doxazosin EP Impurity F
- Doxazosin impurity F, European Pharmacopoeia (EP)
- PRAZOSIN HYDROCHLORIDE IMPURITY A (EP IMPURITY)
- TERAZOSIN HYDROCHLORIDE DIHYDRATE IMPURITY A (EP IMPURITY)
- Terazosin EP Impurity A; Alfuzosin EP Impurity B; Doxazosin EP Impurity F; Prazosin EP Impurity A
- Terazosin EP Impurity ADoxazosin EP Impurity F
- Terazosin impurity A, European Pharmacopoeia (EP)
- DOXAZOSIN MESILATE IMPURITY F
- Doxazosin Related Compound C
- Doxazosin impurity F CRS
- Prazosin impurity A CRS
- quinazolinamine
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