C2H3N3S2
133.2 g/mol
Pharmaceutical IntermediateWarning
5-Amino-1,3,4-thiadiazole-2-thiol
CAS2349-67-9EC219-078-4
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
5-Amino-1,3,4-thiadiazole-2-thiol is a chemical compound used as a reference impurity in the manufacturing and quality control of the pharmaceutical intermediate acetazolamide. It is characterized by a five-membered aromatic ring containing sulfur and nitrogen atoms, along with an amine group, which contributes to its polarity and specific analytical profile.
Reference impurity for acetazolamide preparationResearch compound for pharmaceutical intermediate analysis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 2349-67-9
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Referencestereoisomer of
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Referencesame scaffold
2-Mercapto-5-methyl-1,3,4-thiadiazole
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Referencesame scaffold
2-acetylamino-5-mercapto-1,3,4-thiadiazole
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Referencesame scaffold
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Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
5-amino-3H-1,3,4-thiadiazole-2-thione
InChIKey
GDGIVSREGUOIJZ-UHFFFAOYSA-N
SMILES
C1(=NNC(=S)S1)N
Synonyms (35)
- Acetazolamide EP Impurity G
- 2-Amino-5-mercaptothiadiazole
- 2-amino-5-mercapto-1
- ACETAZOLAMIDE IMPURITY G
- USAF PD-25