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Home/Compounds/Pharmaceutical Intermediate/2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine
C13H10F3N3O5
345.23 g/mol
Pharmaceutical Intermediate

1-(7,8-Dinitro-1,2,4,5-tetrahydro-3H-1,5-methano-3-benzazepin-3-yl)-2,2,2-trifluoroethan-1-one

CAS230615-59-5
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate

This compound is a pharmaceutical intermediate used in the manufacture of varenicline. It is a trifluoroacetyl-protected dinitro derivative with a fused tricyclic ring system containing both aromatic and aliphatic components.

Pharmaceutical intermediate for varenicline synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

(3S,4R)-3-fluoro-1-methyl-piperidin-4-amine;dihydrochloride

CAS2306246-40-0

pharmaceutical intermediate

ReferenceSame Category

Tert-butyl (3R)-4,4-difluoro-3-hydroxy-piperidine-1-carboxylate

CAS2306249-01-2

pharmaceutical intermediate

ReferenceSame Category

(3R,4S)-3-Fluoro-1-methylpiperidin-4-amine dihydrochloride

CAS2306254-06-6

pharmaceutical intermediate

ReferenceSame Category

1-(2-Chloro-5-nitrophenyl)ethanone

CAS23082-50-0

pharmaceutical intermediate

Referencesame scaffold

2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine

CAS230615-69-7

research compound

Referencesame scaffold

2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine

CAS230615-51-7

research compound

Referencesame scaffold

2,3,4,5-tetrahydro-1,5-methano-1H-3-benzazepine hydrochloride

CAS230615-52-8

research compound

Customs Tariff Classification

The international HS code for 1-(7,8-Dinitro-1,2,4,5-tetrahydro-3H-1,5-methano-3-benzazepin-3-yl)-2,2,2-trifluoroethan-1-one (CAS 230615-59-5) is 2933.39.

HS code (international, 6-digit)

2933.39

EU CN code (8-digit)

2933 39 99

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

1-(4,5-dinitro-10-azatricyclo[6.3.1.02,7]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoroethanone

InChIKey

BDTXJBWOCIFUMR-UHFFFAOYSA-N

SMILES

C1C2CN(CC1C3=CC(=C(C=C23)[N+](=O)[O-])[N+](=O)[O-])C(=O)C(F)(F)F

Synonyms (15)
  • Varenicline Ortho-Dinitro

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