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Home/Compounds/API/Sotorasib
C30H30F2N6O3
560.6 g/mol
API

Sotorasib

CAS2296729-00-3
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Sotorasib is a synthetic compound used as an active pharmaceutical ingredient. It acts as an inhibitor of the RAS GTPase family and is investigated for its role in targeting the G12C mutation in the KRAS protein associated with certain cancers.

Active pharmaceutical ingredient for targeted cancer researchResearch compound for KRAS G12C mutation studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Sotorasib

CAS2252403-56-6

pharmaceutical raw material

ReferenceSame Category

15-oxoprostaglandin E1

CAS22973-19-9

pharmaceutical raw material

ReferenceSame Category

Riociguat metabolite M3

CAS2298383-24-9

pharmaceutical raw material

ReferenceSame Category

Atazanavir sulfate

CAS229975-97-7

pharmaceutical raw material

ReferenceSame Category

Terbutaline

CAS23031-25-6

pharmaceutical raw material

Customs Tariff Classification

The international HS code for Sotorasib (CAS 2296729-00-3) is 2933.59.

HS code (international, 6-digit)

2933.59

EU CN code (8-digit)

2933 59 95

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-propan-2-yl-3-pyridinyl)-4-[(2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one

InChIKey

NXQKSXLFSAEQCZ-SFHVURJKSA-N

SMILES

C[C@H]1CN(CCN1C2=NC(=O)N(C3=NC(=C(C=C32)F)C4=C(C=CC=C4F)O)C5=C(C=CN=C5C(C)C)C)C(=O)C=C

Synonyms (30)
  • (S)-AMG-510
  • 2296729-00-3 (racemate)
  • AMG-510 racemate
  • AMG-510(Sotorasib)
  • Kras G12C inhibitor 9
  • Kras mutant-targeting AMG 510
  • Lumakras
  • Lumykras
  • SOTORASIB RACEMATE
  • Sotolasib
  • Sotorasib
  • Sotorasib (AMG510)
  • Sotorasib isomer
  • sotorasibum

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