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Home/Compounds/Research Reagent/N-(3-Methylbutanoyl)alanyl-N-[4-(difluoromethyl)-2-oxo-2H-1-benzopyran-7-yl]-alpha-asparagine
C33H36F3N5O10
719.7 g/mol
Research Reagent

Ac-YVAD-AFC

CAS219137-85-6
Category
Research Reagent
Compound Class
Peptide
Primary Use
Research Compound

Ac-YVAD-AFC is a fluorogenic caspase substrate used in research. It contains a peptide sequence recognized by caspase-1 and related enzymes, and its cleavage releases a fluorescent AFC group for detection.

Fluorogenic substrate for caspase activity assaysResearch tool for studying inflammatory and apoptotic pathways

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxo-4-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]butanoic acid

InChIKey

GWKJISJKNKIJNP-DEQDFGQZSA-N

SMILES

C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C(F)(F)F)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)C

Synonyms (9)
  • Ac-Tyr-Val-Ala-Asp-AFC
  • Ac-YVAD-AFC