C6H12ClNO2
165.62 g/mol
Pharmaceutical IntermediateWarning
Methyl L-prolinate hydrochloride
CAS2133-40-6EC218-363-0
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate
Methyl L-prolinate hydrochloride is a chemical compound used as a pharmaceutical intermediate, primarily in peptide synthesis. It is the hydrochloride salt of L-proline methyl ester, commonly employed as a building block for introducing proline residues into peptide chains.
Pharmaceutical intermediate for peptide synthesisBuilding block in solid-phase peptide synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongStructure SimilarSimilarity 0.88
(R)-Piperidine-2-carboxylic acid methyl ester hydrochloride
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ReferenceSame Category
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pharmaceutical intermediate
ReferenceSame Category
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pharmaceutical intermediate
ReferenceSame Category
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pharmaceutical intermediate
ReferenceSame Category
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pharmaceutical intermediate
Referencestereoisomer of
Methyl D-prolinate
CAS43041-12-9
research compound
Referencestereoisomer of
Methyl D-prolinate hydrochloride
CAS65365-28-8
research compound
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
Customs Tariff Classification
The international HS code for Methyl L-prolinate hydrochloride (CAS 2133-40-6) is 2933.99.
HS code (international, 6-digit)
2933.99
EU CN code (8-digit)
2933 99 80
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
methyl (2S)-pyrrolidine-2-carboxylate;hydrochloride
InChIKey
HQEIPVHJHZTMDP-JEDNCBNOSA-N
SMILES
COC(=O)[C@@H]1CCCN1.Cl
Synonyms (36)
- H-L-PRO-OME HCL
- H-Pro-OMe hydrochloride
- H-Pro-OMe.HCl
- L-Proline methyl ester HCl
- Methyl L-prolinate HCl
- Pro-OMe hydrochloride
- methyl prolinate HCl
- methyl proline hydrochloride
- proline methyl ester HCl salt
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