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Home/Compounds/API/Pralsetinib
C27H32FN9O2
533.6 g/mol
API

Pralsetinib

CAS2097132-94-8
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Pralsetinib is a tyrosine kinase inhibitor used as an active pharmaceutical ingredient in the manufacture of oral medications. It is supplied as a research compound or pharmaceutical raw material for use in drug development and manufacturing processes.

research compound for RET kinase inhibitor studiespharmaceutical raw material for oral dosage form manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

N-[(1S)-1-[6-(4-fluoropyrazol-1-yl)-3-pyridinyl]ethyl]-1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]cyclohexane-1-carboxamide

InChIKey

GBLBJPZSROAGMF-SIYOEGHHSA-N

SMILES

CC1=CC(=NN1)NC2=NC(=NC(=C2)C)C3CCC(CC3)(C(=O)N[C@@H](C)C4=CN=C(C=C4)N5C=C(C=N5)F)OC

Synonyms (29)
  • Pralsetinib (USAN/INN)
  • 2097132-94-8 (free base)
  • BLU-667 (Pralsetinib)
  • Gavreto
  • Gavreto (TN)
  • Pralsetinib
  • Pralsetinib (BLU-667)
  • Pralsetinib (Standard)
  • Pralsetinib free base
  • Pralsetinib, cis-
  • Pralsetinib, trans-
  • US10584114, Compound 129
  • US10584114, Compound 130
  • cis-Pralsetinib
  • trans-Pralsetinib