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Home/Compounds/API/Sirpiglenastat
C22H27N5O5
441.5 g/mol
API

Sirpiglenastat

CAS2079939-05-0
Category
API
Compound Class
Peptide
Primary Use
Pharmaceutical Raw Material

Sirpiglenastat, also known as DRP-104, is a prodrug of 6-diazo-5-oxo-L-norleucine (DON), a broad-acting glutamine antagonist. It is under investigation in clinical trials for advanced solid tumors.

research compound for glutamine antagonist studiespharmaceutical raw material for prodrug development

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

propan-2-yl (2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-6-diazo-5-oxohexanoate

InChIKey

LQNMCWOJACNQQM-PMACEKPBSA-N

SMILES

CC(C)OC(=O)[C@H](CCC(=O)C=[N+]=[N-])NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)C

Synonyms (8)
  • Sirpiglenastat (USAN)
  • Glutamine Antagonist DRP-104
  • Sirpiglenastat