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Home/Compounds/Pharmaceutical Intermediate/2'-O,4'-C-Methylenecytidine
C10H13N3O5
255.23 g/mol
Pharmaceutical Intermediate

2'-O,4'-C-Methylenecytidine

CAS206055-69-8
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

2'-O,4'-C-Methylenecytidine is a locked nucleic acid (LNA) nucleoside analog used as a pharmaceutical raw material in the synthesis of oligonucleotides. It is a key intermediate in the production of compounds such as miravirsen, which has been investigated for research applications.

Pharmaceutical raw material for oligonucleotide synthesisIntermediate in locked nucleic acid (LNA) chemistry

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

LNA-Adenosine

CAS206055-70-1

pharmaceutical intermediate

ReferenceSame Category

N-(9-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-9H-purin-6-yl)benzamide

CAS206055-74-5

pharmaceutical intermediate

ReferenceSame Category

(1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite

CAS206055-76-7

pharmaceutical intermediate

ReferenceSame Category

(1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2-isobutyramido-6-oxo-3H-purin-9(6H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite

CAS206055-77-8

pharmaceutical intermediate

Referencesame scaffold

Lithuanian Film Center

CAS847650-87-7

pharmaceutical intermediate

Identifiers
IUPAC Name

4-amino-1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]pyrimidin-2-one

InChIKey

FCMRQQIZHFHCNG-JIOCBJNQSA-N

SMILES

C1[C@]2([C@H]([C@@H](O1)[C@@H](O2)N3C=CC(=NC3=O)N)O)CO

Synonyms (5)
  • 2'-O,4'-C-Methylenecytidine