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Home/Compounds/Pharmaceutical Intermediate/2-thiouridine
C9H12N2O5S
260.27 g/mol
Pharmaceutical Intermediate

2-thiouridine

CAS20235-78-3
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

2-Thiouridine is a nucleoside analogue in which the carbonyl oxygen at the C-2 position of uridine is replaced by a sulfur atom. This modification classifies it as a thiouridine and a key intermediate utilized in the synthesis of modified RNA molecules for research applications.

intermediate for nucleoside analogue manufacturingresearch compound for RNA modification studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one

InChIKey

GJTBSTBJLVYKAU-XVFCMESISA-N

SMILES

C1=CN(C(=S)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O

Synonyms (16)
  • 2TU
  • 2-thiouridine
  • 3sfg
  • Uridine, 2-thio-
  • s2U